p-Toluenesulfonic acid - Wikipedia
p-Toluenesulfonic acid (PTSA, pTSA, or pTsOH) or tosylic acid (TsOH) is an organic compound with the formula CH 3 C 6 H 4 SO 3 H. It is a white extremely hygroscopic solid that is soluble in water, alcohols, and other polar organic solvents. [6] The CH 3 C 6 H 4 SO 2 group is known as the tosyl group and is often abbreviated as Ts or Tos.
9.4: Tosylate—Another Good Leaving Group - Chemistry LibreTexts
Chlorides, bromides, and tosylate / mesylate groups are excellent leaving groups in nucleophilic substitution reactions, due to resonance delocalization of the developing negative charge on the leaving oxygen.
Tosylate | C7H7O3S- | CID 85570 - PubChem
Tosylate | C7H7O3S- | CID 85570 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Tosylates And Mesylates - Master Organic Chemistry
2015年3月10日 · Another popular option is using the conjugate base of p -toluenesulfonic acid, (“p-toluenesulfonate”) commonly called “tosylate” and abbreviated OTs. These groups have essentially identical leaving group ability and for our purposes are interchangeable.
Tosyl group - Wikipedia
In organic chemistry, a toluenesulfonyl group (tosyl group, abbreviated Ts or Tos[nb 1]) is a univalent functional group with the chemical formula −SO2−C6H4−CH3. It consists of a tolyl group, −C6H4−CH3, joined to a sulfonyl group, −SO2−, with the open valence on sulfur.
p-Toluenesulfonic acid | C7H7SO3H | CID 6101 - PubChem
Toluene-4-sulfonic acid is an arenesulfonic acid that is benzenesulfonic acid in which the hydrogen at position 4 is replaced by a methyl group. It is a member of toluenes and an arenesulfonic acid. It is a conjugate acid of a toluene-4-sulfonate. See also: Abexinostat (part of). 4-methylbenzenesulfonic acid.
17.6: Reactions of Alcohols - Chemistry LibreTexts
Remember that when an alcohol reacts with tosyl chloride to form a tosylate, it is the O-H bond of the alcohol that is broken, not the C-O bond. This means that the absolute configuration of the carbon atom attached to the hydroxyl group remains unchanged throughout the reaction.
14.3: Alcohol conversion to Esters - Tosylate and Carboxylate
We can transform an alcohol group into a sulfonic ester using para -toluene sulfonyl chloride (Ts-Cl) or methanesulfonyl chloride (Ms-Cl), creating what is termed an organic tosylate or mesylate:
p-Toluenesulfonic acid monohydrate | C7H10O4S - PubChem
p-Toluenesulfonic acid monohydrate | C7H10O4S | CID 521998 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
tosylate_化工百科 - ChemBK
Tosylate通常作为有机合成中的离子活化剂，用于有机合成反应中的取代反应、亲核加成反应等。 Tosylate通常通过对甲苯磺酸（Tosic acid）和相应胺类化合物反应来合成。 具体合成方法可根据具体需要进行调整。 使用时应戴好防护手套、护目镜等个人防护装备。 在操作过程中应避免吸入或接触皮肤，如不慎接触应立即用大量清水冲洗。 如有误食或误吸入等意外情况发生，应立即就医。 最后更新：2024-04-09 19:07:33. 中文名:tosylate,英文名:tosylate,CAS:2306313-16-4,化学 …