Structure of the ER membrane complex, a transmembrane …
2020年6月3日 · The endoplasmic reticulum (ER) membrane complex (EMC) cooperates with the Sec61 translocon to co-translationally insert a transmembrane helix (TMH) of many multi-pass …
The ER membrane protein complex is a transmembrane domain …
2017年12月14日 · This ER membrane protein complex (EMC) inserts transmembrane domains whose topology and hydrophobicity preclude effective recognition by other insertion factors. …
The Function, Structure, and Origins of the ER Membrane Protein Complex ...
2022年6月21日 · The endoplasmic reticulum (ER) is the site of membrane protein insertion, folding, and assembly in eukaryotes. Over the past few years, a combination of genetic and …
The mechanisms of integral membrane protein biogenesis
2021年9月23日 · The Sec61 complex (termed the ‘SecY complex’ in bacteria and archaea) is a universally conserved protein conducting channel used for both secretion and membrane …
Integrative modeling of membrane-associated protein assemblies
2020年12月4日 · In this work, we present an integrative computational approach for modeling membrane-associated protein assemblies (complexes consisting of a membrane-embedded …
The ER membrane protein complex interacts cotranslationally to ... - eLife
2018年5月29日 · The ER membrane protein complex (EMC) has emerged as an intriguing player in membrane protein biogenesis in the ER. The EMC was first described in yeast as a complex …
Structural basis for membrane insertion by the human ER membrane …
The nine-subunit endoplasmic reticulum (ER) membrane protein complex (EMC) is a conserved co- and posttranslational insertase at the ER. We determined the structure of the human EMC …
ER membrane complex (EMC): Structure, functions, and roles in …
2024年3月18日 · The ER membrane complex (EMC) on the ER membrane is an ER multiprotein complex that affects the quality control of membrane proteins, which is abundant and widely …
ER membrane complex (EMC): Structure, functions, and roles in
2024年3月31日 · The ER membrane complex (EMC) on the ER membrane is an ER multiprotein complex that affects the quality control of membrane proteins, which is abundant and widely …
The ER membrane protein complex subunit - Springer
2021年6月10日 · The endoplasmic reticulum (ER) membrane protein complex (EMC) regulates the synthesis and quality control of membrane proteins with multiple transmembrane domains. …