Chemically induced mouse models of acute and chronic ... - Nature
2014年6月8日 · In TNBS and oxazolone colitis models, topical administration of hapten reagents results in T-cell-mediated immunity against haptenized proteins and luminal antigens. By …
Dextran sulfate sodium (DSS)-induced colitis in mice - PubMed
2014年2月4日 · Among various chemically induced colitis models, the dextran sulfate sodium (DSS)-induced colitis model is widely used because of its simplicity and many similarities with …
The development of colitis in Il10 −/− mice is dependent on IL-22
2020年1月13日 · These data suggest that spontaneous colitis in Il10−/− mice is driven by IL-22 and implicates an underappreciated IL-10/IL-22 axis in regulating intestinal homeostasis.
The TNBS-induced colitis animal model: An overview - PMC
IL-17 receptor KO mice are shown to resist against TNBS colitis. Recent findings point towards a prominent role of Th17 cells in the pathogenesis of TNBS-induced colitis. Specifically, absence …
DSS-induced colitis is associated with adipose tissue ... - Nature
2021年3月5日 · Both younger and older mice treated with acute or chronic dextran sodium sulfate (DSS) developed colitis, which was evidenced by weight loss, colon length shortening, and …
Mouse models of acute and chronic colitis - PubMed
DSS-induced intestinal inflammation in mice and T cell transfer colitis in SCID mice are most widely used and accepted models that can recapitulate the human diseases. Here, we provide …
Summary of colitis mouse models in IBD research - Taconic
2019年3月19日 · Various animal models, particularly colitis mouse models, are utilized to study IBD mechanisms and develop therapeutic strategies. Controlling the microbiome is crucial for …
Mouse Models of Acute and Chronic Colitis | SpringerLink
2014年1月1日 · DSS-induced intestinal inflammation in mice and T cell transfer colitis in SCID mice are most widely used and accepted models that can recapitulate the human diseases. …
Dextran Sodium Sulphate Colitis Mouse Model: Traps and Tricks
2012年5月14日 · DSS-induced colitis is nowadays frequently used in genetically engineered mice (GEM), to study basic immunologic mechanisms of IBD and to elucidate the role of particular …
Alleviation of DSS-induced colitis in mice by a new-isolated ...
2023年4月19日 · Our data showed that oral administration of L. acidophilus C4 remarkably alleviated colitis symptoms in mice and minimized colon tissue damage. Methods: To elucidate …