15.13: Amides- Structures and Names - Chemistry LibreTexts
2022年9月15日 · Amides have a general structure in which a nitrogen atom is bonded to a carbonyl carbon atom. The functional group for an amide is as follows: In names for amides, the -ic acid of the common name or the -oic ending of the IUPAC for the corresponding carboxylic acid is replaced by -amide.
21.7: Chemistry of Amides - Chemistry LibreTexts
The carbonyl bond is reformed along with the elimination of an amide ion (-NHR) leaving group (note this is a different use of the word amide meaning an amine anion), forming a carboxylic acid. In the last step, the amide ion deprotonates the carboxylic acid to form a carboxylate salt and an amine as products.
The Amide Functional Group: Properties, Synthesis, and Nomenclature
2018年2月28日 · “Amides” are what we call an amine that has a single attached carbonyl group. The amide functional group is to amines as esters are to alcohols. Confusingly, the word “amide” is also used to refer to the conjugate base of amines, such as sodium amide (NaNH 2) and lithium di-isopropyl amide (LDA).
Amide: Definition, Structure, Nomenclature, and Examples
An amide is a fundamental class of organic compounds characterized by their distinct chemical structure, consisting of a carbonyl group (C=O) bonded to a nitrogen atom (N). This carbonyl-nitrogen linkage is a defining feature of amides and imparts unique properties and reactivity to these compounds [1-4] .
26.5 Amides – Structures, Properties and Naming
Amides are molecules that contain nitrogen atoms connected to the carbon atom of a carbonyl group. If the two remaining bonds on the nitrogen atom are attached to hydrogen atoms, the compound is a simple amide .
21.7 Chemistry of Amides - Organic Chemistry - OpenStax
Basic hydrolysis occurs by nucleophilic addition of OH – to the amide carbonyl group, followed by elimination of amide ion (– NH 2) and subsequent deprotonation of the initially formed carboxylic acid by ammonia. The steps are reversible, with the equilibrium shifted toward product by the final deprotonation of the carboxylic acid.
Amides contain carbonyl (C=O) and ether (N-C) dipoles arising from covalent bonding between electronegative oxygen and nitrogen atoms and electro-neutral carbon atoms. Primary and secondary amides also contain two- and one N-H dipoles, respectively.
24.6: Compounds with a Carbonyl Group - Chemistry LibreTexts
In amides, the carbonyl carbon is bonded to a nitrogen. The nitrogen in an amide can be bonded either to hydrogens, to carbons, or to both. Another way of thinking of an amide is that it is a carbonyl bonded to an amine. In esters, the carbonyl carbon is bonded to an oxygen which is itself bonded to another carbon. Another way of thinking of an ...
Amide Definition and Examples in Chemistry - Science Notes and …
2022年12月6日 · In chemistry, an amide is either an organic functional group with a nitrogen atom bonded to a carbonyl carbon atom or a compound containing nitrogen bonded to carbon (or another atom) and two other groups. An amide is a derivative of an oxoacid [R n E(=O) x OH), where n and x are 1 or 2, E is an element, and R is hydrogen or an organic group ...
7.4 Esters and Amides – Introductory Organic Chemistry
Amides have electronegative nitrogen atoms, with their lone pair electrons in a position close to the carbonyl group. This arrangement produces molecules with some polarity, but the degree of polarity in an amide is also influenced by what connects to the nitrogen itself. In short, polarity can vary a lot within this family of compounds.