Botulinum toxin - Wikipedia
Botulinum toxin, or botulinum neurotoxin (commonly called botox), is a neurotoxic protein produced by the bacterium Clostridium botulinum and related species. [24] It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction, thus causing flaccid paralysis. [25] The toxin causes the disease ...
肉毒桿菌毒素 - 维基百科，自由的百科全书
肉毒桿菌毒素 （botulinum toxin，BTX）又称 肉毒毒素[1] 、 肉毒神经毒素 （botulinum neurotoxin）、 肉毒杆菌素，是由 肉毒杆菌 于厭氧條件下生長时所產生的一类高分子蛋白质的 神经毒素，主要抑制 神经末梢 释放 乙酰胆碱，引起肌肉松弛麻痹。 一克肉毒桿菌毒素，通过注射就能杀死一千万人，是人类已知的最强毒素。 [2] 肉毒杆菌毒素共有A、B、Cα、Cβ、D、E、F、G八種類型，其中A型、B型、E型、F型对人类有毒性，大剂量可致死，但低剂量局部使用可消除 …
Botulism - World Health Organization (WHO)
2023年9月25日 · Botulinum toxins are one of the most lethal substances known. Botulinum toxins block nerve functions and can lead to respiratory and muscular paralysis. Human botulism may refer to foodborne botulism, infant botulism, wound botulism, and inhalation botulism or other types of intoxication.
肉毒毒素 - 百度百科
肉毒毒素（botulinum toxin，BX）是肉毒杆菌产生的含有高分子蛋白的神经毒素，是已知在天然毒素和合成毒剂中毒性最强烈的生物毒素，它主要抑制神经末梢释放乙酰胆碱，引起肌肉松弛麻痹，特别是呼吸肌麻痹是致死的主要原因。
Botulinum Toxin - StatPearls - NCBI Bookshelf
2023年11月6日 · Botulinum toxin is a medication used to manage and treat therapeutic and cosmetic purposes. Medicinal uses include chronic migraine, spastic disorders, cervical dystonia, and detrusor hyperactivity. Botulinum toxin is in the neurotoxin class of medications.
Botulinum toxin | Description, Neurotoxicity, Symptoms, …
2024年11月6日 · botulinum toxin, poisonous protein made by Clostridium botulinum and several closely related species of bacteria that causes botulism, a condition characterized by neurotoxicity, primarily muscle paralysis. Botulinum toxin …
Clinical Uses of Botulinum Neurotoxins: Current Indications ...
Botulinum neurotoxins (BoNTs) cause flaccid paralysis by interfering with vesicle fusion and neurotransmitter release in the neuronal cells. BoNTs are the most widely used therapeutic proteins.
About Botulism | Botulism | CDC - Centers for Disease Control …
2024年4月18日 · Botulism ("BOT-choo-liz-um") is a rare but serious illness caused by a toxin that attacks the body's nerves. Botulism causes difficulty breathing, muscle paralysis, and even death. The toxin is made by Clostridium botulinum and sometimes Clostridium butyricum and Clostridium baratii bacteria (germs). These bacteria can produce the toxin in food ...
Botulinum Neurotoxins: Biology, Pharmacology, and Toxicology
Botulinum neurotoxins (BoNTs) are protein neurotoxins produced by neurotoxigenic strains of anaerobic and spore forming bacteria of the genus Clostridium (Clostridium botulinum, Clostridium butyrricum, Clostridium barati, and Clostridium argentinensis) (Smith et al., 2015).
Botulinum toxin the poison that heals: A brief review - PMC
The neurotoxin called botulinum toxin (BT) is produced by the bacterium Clostridium botulinum. This toxin is capable of causing muscle paralysis by blocking the release of Ach at the neuromuscular (NM) junction of striated muscle.