Antifungal susceptibility testing: applicability of methods and ...
2024年9月18日 · We outline seven steps for implementation of AFST with an initial focus on accurate species identification (to predict intrinsic resistance) of Candida albicans, Candida …
Antifungal Susceptibility Testing: Current Approaches
The goal of AFST is to reliably produce MIC values that may be used to guide patient therapy, inform epidemiological studies, and track rates of antifungal drug resistance. There are three …
How to: EUCAST recommendations on the screening
2019年6月1日 · Prepare antifungal drug stock solutions in DMSO at concentrations at least 200 times higher than the concentration to be tested in the agar plate (see example below). …
Standardisation of high throughput microdilution antifungal ...
2024年10月8日 · In this study we compared conditions from the CLSI guidelines with conditions described in the literature, such as alternative temperature, media and incubation time, and we …
Antifungal susceptibility testing - UpToDate
2023年1月27日 · The need for reproducible, clinically relevant antifungal susceptibility testing has been prompted by the increasing number of invasive fungal infections, the expanding use of …
Tackling the emerging threat of antifungal resistance to human …
2022年3月29日 · In this Review, we highlight the main mechanisms of antifungal resistance and explore the similarities and differences between bacterial and fungal resistance to …
Antifungal Resistance Testing and Implications for Management
2019年10月23日 · We review the strengths and weaknesses of antifungal susceptibility testing and how the detection of resistance, either phenotypically or molecularly, correlates with …
Fungal Biofilm Resistance - PMC - National Center for …
2012年2月8日 · This paper aims to illustrate the importance of fungal biofilms, particularly Candida albicans, and discusses some of the key fungal biofilm resistance mechanisms that …
Confronting antifungal resistance, tolerance, and persistence: …
2023年9月1日 · In this review we summarize recent advances in the study of antifungal resistance, tolerance and persistence, with an emphasis on promising drug targets and drug …
Most azole resistance mutations in the - Nature
2024年10月8日 · Deep mutational scanning of the azole antifungals drug target Erg11 provides an extensive catalogue of resistance mutations and reveals that resistance to azoles can arise …