Mitochondrial dysfunction in kidney injury, inflammation, and …
Recent literature suggests that alterations in mitochondrial dynamics are implicated in kidney injury and the progression of kidney diseases. A decrease in mitochondrial fusion promotes …
Mitochondrial energetics in the kidney - Nature Reviews …
2017年8月14日 · This Review discusses how mitochondrial homeostasis is maintained, the changes in mitochondrial energetics that occur in acute kidney injury and diabetic …
Mitochondrial quality control in kidney injury and repair
2020年11月24日 · Given the critical role of mitochondrial dysfunction in kidney injury and abnormal kidney repair, specific interventions that target mitochondrial quality control …
Mitochondria Damage and Kidney Disease - PMC - National …
In this chapter, we discuss evidence supporting mitochondrial dysfunction in the pathogenesis of kidney disease, and summarize the recent development of mitochondria-targeted therapies …
Mitochondrial energetics in the kidney - PubMed
The kidney requires a large number of mitochondria to remove waste from the blood and regulate fluid and electrolyte balance. Mitochondria provide the energy to drive these important …
New evidence of the impact of mitochondria on kidney health
2023年12月14日 · Analyses of kidney biopsy samples from humans and mice have shown that alterations in NAD synthesis in the context of kidney injury leads to mitochondrial dysfunction …
The Hallmarks of Mitochondrial Dysfunction in Chronic Kidney …
2019年11月17日 · We will examine the current understanding on the molecular mechanisms that cause mitochondrial dysfunction in the kidney and describe the impact of mitochondrial …
The Role of Mitochondria in Acute Kidney Injury and Chronic Kidney …
2021年10月19日 · The kidney is an organ enriched in mitochondria and with high energy demand in the human body. Recent studies have been focusing on how mitochondrial dysfunction …
The role of mitochondrial dysfunction in kidney injury and disease
2024年6月1日 · In this review, we integrate the role of mitochondrial dysfunction in different kidney diseases, and specifically elaborate the mechanism of mitochondrial reactive oxygen …
The multifaceted role of kidney tubule mitochondrial dysfunction …
The kidney has one of the highest mitochondrial density. Mitochondrial biogenesis, mitochondrial fusion, fission, and mitochondrial recycling, such as mitophagy are critical for proper …