Table 1, Statin Dosing and ACC/AHA Classification of Intensity - Statin …
Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: A Systematic Review for the U.S. Preventive Services Task Force [Internet]. From ACC/AHA, 2018. 199 Dosages shown are total daily dosages; exceptions are noted.
Understanding statin intensity - Harvard Health
2023年7月1日 · For example, 10 or 20 mg of atorvastatin daily is considered moderate intensity, while 40 to 80 mg is high intensity. The choice of a statin depends on a person's risk. For someone with high LDL but no other risk factors or evidence of coronary artery disease, moderate-intensity therapy makes sense.
Cholesterol Management: ACC/AHA Updates Guideline - AAFP
2019年5月1日 · Based on high-quality evidence from randomized controlled trials (RCTs), high-intensity statin therapy should be instituted with a goal of lowering LDL-C levels by 50% or more in patients...
ASCVD risk, begin high-intensity statin therapy. If the LDL-C level remains ≥100 mg/dL (≥2.6 mmol/L), adding ezetimibe is reasonable. If the LDL-C level on statin plus ezetimibe remains ≥100 mg/dL (≥2.6 mmol/L) and the patient has multiple factors that increase subsequent risk of ASCVD events, a PCSK9 inhibitor may be consid-
2019 ACC/AHA Guideline on the Primary Prevention of …
2019年3月17日 · If in the context of a risk discussion, maximal ASCVD risk reduction is desired, it is reasonable to use a high-intensity statin to lower LDL-C by ≥50%. This provides increased benefit, especially when 10-year ASCVD risk is ≥20%.
High-Intensity Statins Benefit High-Risk Patients: Why and …
2021年9月14日 · High-intensity statins are recommended for 2 categories of patients: those with ASCVD (secondary prevention) and high-risk patients without clinical ASCVD. Most patients with ASCVD are candidates for high-intensity statins, with a goal for low-density lipoprotein cholesterol reduction of 50% or greater.
ACC/AHA Release Updated Guideline on the Treatment of Blood Cholesterol …
2014年8月15日 · Persons 21 years or older who have LDL-C levels of 190 mg per dL or greater should be treated with statin therapy. High-intensity statins should be used unless contraindicated.
What Are High Intensity Statins, and When Are They Used? - GoodRx
2022年1月19日 · Statins are medications used to lower bad cholesterol levels. “High intensity” statins are the strongest within the class. Certain strengths of Lipitor and Crestor are considered high intensity statins. Learn more about high intensity statins and when they’re used with GoodRx.
cholesterol management (refer to chart for full guidelines) • In patients with severe primary hypercholesterolemia (LDL-C level ≥190 mg/dL preeclampsia, premature menopause) (≥4.9 mmol/L)), begin high-intensity statin therapy without calculating 10-year ASCVD risk. • In patients 40 to 75 years of age with diabetes
Evidence review for statins: efficacy and adverse effects
High-intensity statins showed a benefit for reduced rates of CVD events compared to low- or medium-intensity statins. A newly added study comparing atorvastatin 40mg and 20 mg suggested a consistent benefit of the 40 mg dose for all outcomes.