Physiology, Cardiac - StatPearls - NCBI Bookshelf
2023年7月30日 · The pathophysiology of the heart is complex, and as such, several examples will be illustrated to give a basic understanding of the mechanism of changes. To begin, we will discuss heart failure (HF) in the context of two categories: diastolic and systolic heart failure.
Physiology, Cardiovascular - StatPearls - NCBI Bookshelf
2022年10月16日 · The heart and vessels work intricately to provide adequate blood flow to all body parts. The regulation of the cardiovascular system occurs via a myriad of stimuli, including changing blood volume, hormones, electrolytes, osmolarity, medications, adrenal glands, kidneys, and much more.
Congestive Heart Failure - StatPearls - NCBI Bookshelf
2023年11月5日 · Congestive heart failure (CHF) is a complex clinical syndrome characterized by inefficient myocardial performance, resulting in compromised blood supply to the body. CHF results from any disorder that impairs ventricular filling or …
Pathophysiology of Coronary Artery Disease | Circulation
2005年6月28日 · During the past decade, our understanding of the pathophysiology of coronary artery disease (CAD) has undergone a remarkable evolution. We review here how these advances have altered our concepts of and clinical approaches to both the chronic and acute phases of CAD.
What Is the Heart? Anatomy, Function, Pathophysiology, and ...
2018年6月4日 · Torrent Guasp's helical ventricular myocardial band (HVMB) defines this anatomy and its structure, and explains why the heart's six dynamic actions of narrowing, shortening, lengthening, widening, twisting, and uncoiling happen.
Mechanisms and Models in Heart Failure | Circulation Research
2021年5月13日 · To provide the necessary structure for this review, we will begin with a brief overview of the pathophysiology of HFrEF, followed by an overview of the current conceptual models for HFrEF, and end with an analysis of the scientific rationale and clinical development programs for 4 new therapeutic classes of drugs that have improved clinical outc...
CV Physiology | Pathophysiology of Heart Failure
Pathophysiology of Heart Failure. Cardiac dysfunction precipitates changes in vascular function, blood volume, and neurohumoral status. These changes serve as compensatory mechanisms to help maintain cardiac output (primarily by the Frank-Starling mechanism) and arterial blood pressure (by systemic vasoconstriction). However, these compensatory ...
Heart Failure (HF) - Heart Failure (HF) - The Merck Manuals
Cardiac output (CO) is the product of stroke volume and heart rate; it is also affected by venous return, peripheral vascular tone, and neurohumoral factors. Preload is the loading condition of the heart at the end of its relaxation and filling phase (diastole) just before contraction (systole).
Heart Physiology and Pathophysiology | ScienceDirect
Heart Physiology and Pathophysiology, 4E, provides the foundation for the scientific understanding of heart function and dysfunction, and bridges the gap between basic cardiovascular science and clinical cardiology. This comprehensive text covers all the important aspects of the heart and vascular system.
Congestive Heart Failure Pathophysiology - Verywell Health
2024年10月5日 · What Is the Pathophysiology of Heart Failure? Heart failure develops when there are changes to the structure of the heart muscle and it can't pump blood as efficiently as it should. When this happens blood can back up and fluid may build up in the lungs or arms and legs, indicating congestive heart failure.