The San Francisco 49ers are preparing for their Week 13 contest against the Buffalo Bills on Sunday at Highmark Stadium in ...

There's no two ways about it: the San Francisco 49ers are having a brutal season. Taking the field in Week 1 with sky-high ...

The 49ers are set to have quarterback Brock Purdy back in the lineup this weekend. Purdy missed last Sunday's loss to the ...

San Francisco 49ers quarterback Brock Purdy is expected to return Sunday against the Buffalo Bills, head coach Kyle Shanahan ...

The San Francisco 49ers have released their final injury report ahead of their Week 13 bout with the Buffalo Bills.

With the Miami Dolphins taking a 30-17 loss to the Green Bay Packers on Thursday night, the Buffalo Bills can wrap up the AFC East for a fifth straight season o ...

San Francisco 49ers quarterback Brock Purdy will return to the starting lineup Sunday against the Buffalo Bills, Kyle ...

Brock Purdy is expected to return Sunday night against the Bills, but offensive tackle Trent Williams, defensive end Nick ...

The San Francisco 49ers released their latest injury updates headed into the team's Week 13 matchup vs. the Buffalo Bills.

The San Francisco 49ers expect to get quarterback Brock Purdy back for their Week 13 matchup with the Buffalo Bills. That’s ...

San Francisco 49ers quarterback Brock Purdy appears to be making strides in his recovery from a shoulder injury. During the ...

There are no teams on bye around the NFL in Week 13, which means we'll be treated to a packed slate of Sunday games even ...