Otsuka Pharmaceutical Development & Commercialization, Inc. (OPDC) and Otsuka Pharmaceutical, Co. Ltd. (Otsuka) announce the decision to submit a Biologics License Application (BLA) in the U.S. for ...
monoclonal antibodies, such as cetuximab and panitumumab, directed against the extracellular domain of EGFR, and tyrosine kinase inhibitors, like gefitinib and erlotinib, which block the kinase ...
The initial project will focus on antibodies’ design with agonistic function for a demanding GPCR target. Credit: SmartPhotoLab/Shutterstock. Nxera Pharma ...
The delay “does not impact our MRUS thesis,” he added. Petosemtamab is a human, full-length IgG1 monoclonal antibody designed to bind to EGFR and LGR5, both of which are known cancer targets.
of 7.4. Sac-TMT specifically recognizes TROP2 on the surface of tumor cells by recombinant anti-TROP2 humanized monoclonal antibodies, which is then endocytosed by tumor cells and releases ...