Bigner, MD, PhD Faillot and coworkers [21] also performed a phase I study to evaluate whether a single IV injection could deliver an adequate amount of anti-EGFR monoclonal antibody (MAb 425 ...
monoclonal antibodies, such as cetuximab and panitumumab, directed against the extracellular domain of EGFR, and tyrosine kinase inhibitors, like gefitinib and erlotinib, which block the kinase ...