China’s drug regulator approved Alpha Biopharma Ltd.’s EGFR tyrosine kinase inhibitor (TKI), Zorifer (zorifertinib hydrochloride tablets; AZD-3759), as a first-line treatment for EGFR-mutated ...

Johnson & Johnson JNJ announced that the EMA’s Committee for Medicinal Products for Human Use (“CHMP”) recommended approving the combination of its intravenously administered EGFR/MET ...

The term “protease inhibitor” refers to a class of medications rather than to a single medication. Specifically, they are antiviral drugs. But unlike the many, more common antiviral drugs that ...

Skin biopsies from EGFR inhibitor-treated and cicatricial alopecia patients revealed an active JAK ... be exploited by microbes leading to hair follicle inflammation and the consecutive destruction of ...

State Key Laboratory of Green Pesticide, College of Chemistry, Central China Normal University, Wuhan 430079, China ...

Sunvozertinib has shown promising results in patients with non–small cell lung cancer with an EGFR exon 20 insertion mutation. The new drug application (NDA) of sunvozertinib in relapsed/refractory ...

Instead, research is more focused on mechanisms of resistance to first-line TRK inhibitors. “There are now clear mechanisms of resistance with these molecules in the context of certain mutations,” he ...

Department of Molecular Biology & Biochemistry, University of California, Irvine, Irvine, California 92697-3900, United States Department of Pharmaceutical Sciences, University of California, Irvine, ...

Kim’s team revealed that once COVID-19 invades human cells, it quickly modifies the structure and function ... Using FDA-approved EGFR inhibitors, such as vandetanib and dacomitinib, the team ...