The evidence for the authors' claims is convincing, combining state-of-the-art conditional gene deletion in the mouse lens with histological and molecular approaches. This work should be of great ...

Gene expression profiling is the determination of the pattern of genes expressed, at the level of transcription, under specific circumstances or in a specific cell to give a global picture of ...

Human epidermal growth factor receptor 2 (HER2) proteins are found on the surface of breast cells and are ... All women have HER2 genes that code for HER2 proteins, which are involved in the growth of ...

Close Encounters Between Distant DNA Regions Cause Bursts of Gene Activity Dec. 6, 2024 — Researchers have revealed a new mechanism underlying how spatial distance between specific regions of ...

The universal cell-cycle inhibitor p21 Cip1/WAF1 is phosphorylated and localized in the cytoplasm in Her2/neu-overexpressing breast cancers as a result of its physical association with the ...

The MYC gene drives muscle growth and adapts to exercise but wanes with age, affecting recovery. Research shows MYC alone can mimic exercise effects, though its oncogenic risks demand cautious ...

Correspondence to Professor Jun Yu, Institute of Digestive Disease, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China; ...

Researchers at Inventisbio Co. Ltd. and Inventisbio LLC have described Werner syndrome ATP-dependent helicase (WRN; RECQ3; RECQL2) inhibitors reported to be useful for the treatment of cancer.