"The effort of producing high-resolution cryo-EM images is wasted if they are compromised by poor sample preparation," Usukura says. He advises that a good sample for cryo-EM is, most importantly ...

such as cryo-electron microscopy (cryo-EM) single-particle averaging (SPA) analysis, rely on averaging data from thousands of ...

For the first time, researchers at the University of California San Diego report near-atomic-resolution images and video of nitrogenase during catalysis using cryogenic electron microscopy (cryoEM).

Researchers performing cryo-EM experiments can acquire the training to make their own cryo-EM and negative-stain grids, and collect and process their own high-resolution data. We also offer sample ...

“Cryo-EM allows us to peer into a world that we simply ... Subsequently, a 3D map of the target protein is created using ...

This was because the resulting images were little more than blobs - hence the rude description of "blobology" by its detractors. But over time, scientists refined cryo-EM to the point that it ...

This “exposure” yields many 2-D images of the molecules at different angles, which algorithms then merge into one 3-D model. At first cryo-EM rendered molecules as vague lumps, so some ...

Purdue Uni Cryo-EM was used to determine the structure of ... Over a few months, 3-D images of the virus at atomic resolution were generated and researchers could start searching for potential ...

The University of Colorado Boulder Biochemistry Department's Krios Electron Microscopy facility (BioKEM) offers single particle cryo-EM and cryo tomography of plunge-frozen samples. The BioKEM ...