We describe two patients with hypertrophic osteoarthropathy, spider naevi and elevated 24 h urinary oestrogen excretion associated with an adenocarcinoma. In one of the patients, the spider naevi ...

Cutaneous spider nevi (12 cases), finger clubbing (4 cases) and clinical cyanosis (2 cases) had been noted during life. Esophageal varices, indicating portal hypertension, were present in all cases.