Tumor suppressor genes act as “brakes” to stop cells before they can travel down the road to cancer. A loss of function mutation in these genes can be disastrous. Like all genes, tumor ...

When cell growth gets out of control and malignant cells begin to proliferate, cancer can develop in a process known as ...

Martin Fischer was selected from an international pool of nominees for his groundbreaking research on gene regulation by ...

These mechanisms, including those involving the tumor suppressor protein p53, are widely studied due to their critical role ...

Cancer cells exhibit a distinct metabolism compared to normal cells, characterized by enhanced glycolysis and glutaminolysis ...

Corresponding author Richard Kriwacki, PhD, St. Jude Department of Structural Biology, investigated how the tumor suppressor p14 ARF undergoes phase separation with nucleophosmin in the nucleolus ...

Researchers at the University of Ottawa may have cracked the code to harness both mRNA and RNAI-based therapies to improve ...

"This is a tumor suppressor mechanism that had not been described before, and we think the cancers that can turn it off, by ...

Here we present a brief overview of the key tumor suppressors and driver oncogenes involved in NSCLC followed by a review of the most recent and cutting edge studies which are advancing our ...

Synthetic suppressor T cells could improve treatment for organ transplants, type 1 diabetes, and other autoimmune conditions.