RANKL has essential roles in the formation of mammary gland and lymphoid organs by stimulating proliferation or differentiation ... Tumor infiltrating Tregs express RANKL, which promotes bone ...

Additionally, there is an imbalance between T-helper 17 (Th17) cells and regulatory T (Treg) cells, with a lower Treg/Th17 ratio being linked to worse outcomes. Metabolic reprogramming is a ...

optimagic is a Python package for numerical optimization. It is a unified interface to optimizers from SciPy, NlOpt and other packages. optimagic's minimize function works just like SciPy's, so you ...