RECENTLY we have reported that sulphonamides with a substituted amido-group that is, compounds deprived of any inhibitory action on carbonic anhydrase, may possess a high diuretic activity 1.

School of Pathology, Trinity College, Dublin, Ireland.

Department of Chemistry, The University of Manchester, Oxford Road, Manchester M13 9PL, U.K.

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh 33516, Egypt Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Pharos University in ...