When an orally administered drug dissolves, it must cross the intestinal wall, reach the liver via the portal ... mesenteric blood flow. a RYGB = Roux-en-Y gastric bypass, Mct1 = monocarboxylic ...
Purpose Pharmacokinetic considerations in patients who have undergone Roux-en-Y gastric bypass (RYGB ... circulation and are delivered to the liver for metabolism (first-pass metabolism) before ...
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