This important work advances our understanding of DNA methylation and its consequences for susceptibility to DNA damage. This work presents evidence that DNA methylation can accentuate the genomic ...
GT-02287 reduced the level of mitochondrial reactive oxygen species (ROS) as well as ameliorating lysosomal pathology, reducing α-synuclein aggregation, and providing a neuroprotective effect. In an ...
The intricate relationship between diet, metabolic disorders, and cancer progression has garnered significant attention in recent years. Excessive calorie intake is known to trigger the production of ...
1Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts. 2Department of Biological Engineering, Massachusetts Institute of Technology, ...