Roberts in 1958. Subsequent studies by James Watson, Francis Crick, and others revealed the central role of ribosomes in protein synthesis, laying the foundation for our current understanding of these ...
A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER), as reported by researchers at Science Tokyo.
The large subunit rRNA, in particular, is responsible for the peptidyl transferase reaction, which catalyzes the formation of peptide bonds between amino acids during protein synthesis. This discovery ...
This important study by Bi and colleagues employed a clever genetics screen to uncover the role of the GidB rRNA methylase in translation fidelity, under certain conditions, in Mycobacterium smegmatis ...
In eukaryotic cells—found in animals, plants, and fungi—protein synthesis involves more than the simple assembly of amino acids in ribosomes. Nearly ...