In an additional approach, we tested whether highly central RNAs were enriched in single-nucleus sequencing (snRNA-seq), compared to scRNA-seq, which was true for only a subset of genes (Figure ...

Titin’s regulated integration and mobility after cell fusion support syncytium formation in culture, while limited diffusion in vivo highlights a key challenge for developing effective cell-based ...

Carnegie Mellon’s Joel McManus and Pitt’s Robert Nicholls received a $162,000 grant from the Foundation for Prader-Willi Research to study the regulation and function of a key gene that is usually ...

The Leibniz Prize is awarded annually to scientists for their "outstanding achievements in the field of research." ...

Using an innovative approach, EMBL scientists uncovered key interactions between molecular machines, potentially opening new avenues for drug development. Choosing a film for a movie night is always a ...

Insights into protein synthesis processes in prokaryotes and eukaryotes are crucial for advancements in genetics, ...

Adding to the ever-growing list of newly discovered bacterial immune systems, we have characterized the mechanisms of an ...

The Phase 1 trial ANQUR, now testing two new doses of the ALS therapy QRL-201, is enrolling patients at 12 sites in Canada ...

These dominant negative molecules are powerful and their effects cannot be easily compensated by cells. They settled on an mRNA called RUNX1-Trap, which keeps RUNX1 in a cell’s cytoplasm, preventing ...

Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell makes a copy of DNA, called ...