In this valuable study, the authors used an elegant genetic approach to delete EED at the post-neural crest induction stage. The usage of the single-cell RNA-seq analysis method is extremely suitable ...

Here, we used deep full-length single-cell RNA-sequencing to distinguish post-mitotic cone and rod developmental states and cone-specific features that contribute to retinoblastomagenesis. The ...

Scientists at Queen Mary University of London and the University of Hong Kong have created a mouse with substituted genes ...

To this end, they developed a novel embryo-like model system consisting of a layer of epiblast and a layer of VE cells—a cup without a lid. They achieved this with the targeted and controlled ...

The emergence of multicellular life roughly 700 million years ago was a pivotal event that shaped the evolution of life on ...

The protein netrin1 has an entirely unanticipated role in organizing the spinal cord during early development.

We all start our lives as symmetric balls of cells. In humans, during the first few weeks after fertilization, embryonic ...

Researchers have uncovered an unexpected role for the molecule netrin1 in organizing the developing spinal cord.