Pollak, Michael N. Papkovsky, Dmitri B. and Topisirovic, Ivan 2022. Mitochondrial complex IV defects induce metabolic and signaling perturbations that expose potential vulnerabilities in HCT116 cells.

In his book, Jan Vijg gives a very comprehensive ... Vijg describes this genome and discusses the significance of DNA damage to mitochondria, which may be an important signaling factor in the ...

The first section of the book, Cellular DNA Replication ... another 7 are caused by mutations generated during mitochondrial DNA replication, and 38 result from expansion or contraction of ...

known today as mitochondrial DNA (mtDNA). Today mtDNA produces 13 key mitochondrial proteins. As mitochondria age, they change shape and become less active. Eventually they fail and release mtDNA.

Mitochondrial DNA depletion syndrome (MTDPS) is a rare genetic disorder characterized by a marked decrease in mitochondrial DNA (mtDNA).