Gastman, B.R. et al. Fas ligand is expressed on human squamous cell carcinomas of the head and neck, and it promotes apoptosis of T lymphocytes. Cancer Res. 59 , 5356–5364 (1999). CAS PubMed ...

Metabolic stress causes an increased Fas-FasL (receptor-ligand pair) expression in Neural Stem Cells (NSCs) leading to Fas-induced apoptosis. In this study, we discuss the exposure of NSCs to ...

Correspondence to: Dr G J Gores Mayo Clinic College of Medicine, 200 First St SW, Rochester, Minnesota 55905, USA; gores.gregorymayo.edu Apoptosis is a highly organised and genetically controlled type ...

Fas was overexpressed on Tregs during AHA ... San Jose, California, USA); anti-TNF-related apoptosis-inducing ligand (TRAIL)-PE; anti-DR4-APC; anti-DR5-PE (Biolegend, San Diego, California, USA) and ...

However, the interaction between Beclin 1 and Bcl-2/Bax has not been conjunctively analyzed. This review aims to examine the crosstalk between autophagy and apoptosis in ICH by focusing on the ...

Several lines of evidence both from experimental models and from clinical studies reveal that TNF-like ligand 1A (TL1A) and its interaction with death receptor 3 (DR3) is critically involved in ...

In this study, we aim to further reveal its complex pathogenesis by exploring the role of Fas apoptotic inhibitory molecule 2 (FAIM2) in modulating pathological cardiac hypertrophy. We used ...

P2Rank: Protein-ligand binding site prediction from protein structure based on machine learning.

Absence of lymphoid tissue suggests SCID or combined immune deficiency. Lymphadenopathy and hepatosplenomegaly can be seen in antibody deficiencies (eg, common variable immune deficiency, CVID), ...

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The activation of pro-apoptotic p53 and Fas ligand (CD95/Apo1)-mediated pathways ... Key signaling pathways, including those involving p53 and PTEN, that are involved in cell proliferation, apoptosis, ...