A groundbreaking study has used patient-derived stem cells to recreate a rare genetic form of autism in the lab.

This important study introduces rationally designed, genetically encoded tools for the selective and reversible ablation of excitatory and inhibitory synapses. The evidence is convincing, supported by ...

A new study reveals how NREM sleep enhances cognitive performance by synchronizing neural activity and improving information ...

Chofflet et al. investigate the immunoglobulin superfamily member 21 (IgSF21)–neurexin2α (Nrxn2α) complex, a critical organizer of inhibitory synapses in the brain, and provided insights into the ...

Morris, like thousands of other customers, was snared in the collapse of a behind-the-scenes fintech firm called Synapse and has been locked out of her account for six months as of November.

Without effective inhibitory signaling ... a protein essential for presynaptic structure in excitatory, glutamatergic synapses. Lastly, researchers noted a decrease in the amplitude of miniature ...

“Sheila noticed that when applied onto NMDA receptors that were chronically active, ketamine had a stronger inhibitory effect than expected based on the ... “Moreover, the increase in excitation ...

Thus, insights into these aspects of inhibitory inputs can inform us largely on the functions of neural circuits and the brain. Endophilin A1, an endocytic protein heavily expressed in neurons, has ...