Researchers investigating ways to reduce exhaustion in cancer-fighting T-cells found that the Golgi apparatus can be used as a simple marker -- more Golgi means a more robust cell.

as most of them were negative for the T cell markers CD3, CD4 and CCR6; they were, however, positive for mast cell tryptase (MCT), a specific marker of mast cells. Having identified mast cells as ...

Marker Therapeutics was awarded a $2 million grant from NIH Small Business Innovation Research Program (SBIR) to support the clinical investigation of MT-601 in patients with lymphoma who have ...

T cell-based immunotherapies including immune checkpoint blockade and chimeric antigen receptor T cells can induce durable responses in patients with cancer. However, clinical efficacy is limited due ...