TYK Medicines Inc. has identified proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase-binding moiety covalently bonded to an EGFR (mutant)-targeting moiety through a ...
Research indicates that people with a family history of lung cancer have an increases risk, even without direct tobacco exposure. Specific genetic mutations, such as those found in the EGFR gene, are ...