Small molecules - AQA A covalent bond is a shared pair of electrons. Covalent bonding forms molecules. Substances with small molecules have low melting and boiling points, and do not conduct ...

Covalent chemical probes – chemical probes that form a covalent bond with their target biomacromolecule(s) represent powerful tools that can be used for biology discovery, target validation (or ...

Prior to 2000, many drugs that formed a covalent bond with targets did so non-selectively, which often led to undesired side effects when compared to non-covalent drugs. This led to the belief that ...