Researchers at the Centre (CRG) reveal that metabolic enzymes known for their roles in energy production and nucleotide synthesis are taking on unexpected "second jobs" within the nucleus, ...
These gastric cancer cells contain circular fragments of DNA (ecDNA) that encode two different oncogenes, one in red and one in green. Cooperating ecDNAs are often passed into the same cell during ...
The researchers’ findings not only shed new light on these fundamental molecular mechanisms but also suggest potential applications in blood cancer treatment. Tumor cells are notorious for their rapid ...
Tumor cells are notorious for their rapid and uncontrolled division, and many cancer therapies aim to disrupt this process. Often, this leads to the formation and accumulation of multiple ...
Metabolic enzymes, typically associated with energy production, are now discovered to also play essential roles in the nucleus, such as orchestrating cell division and DNA repair. This breakthrough, ...
The Golgi apparatus modifies, sorts and packages proteins to be sent to their final destinations, whether that's within or outside of the cell. It's a core function, but little studied in the ...