These effects are mediated by the activation of the MC4R-cAMP-GLP-1 signaling pathway, highlighting the importance of this molecular pathway in the regulation of glucose metabolism. Furthermore, we ...

leptin signaling intersects with insulin pathways in pancreatic β-cells. When leptin binds to its receptors in these cells, ...

cAMP dynamic and cAMP HiRange), Cisbio allows detection of a broad range of cyclic AMP concentrations. Classically, the GPCR signaling pathway is considered to be a three-component system that ...

"Our study reveals a new pathway of temperature perception in cells. We found that a plasma membrane-localized COLD6-OSM1 module triggered the production of the signalling molecule 2',3'-cAMP ...

Vasoactive Intestinal Peptide (VIP) is an intriguing neuropeptide with a wide range of potential biological impacts, primarily hypothesized in tissues, cells, and internal systems. Since its discovery ...

"Our study reveals a new pathway of temperature perception in cells. We found that a plasma membrane-localized COLD6-OSM1 module triggered the production of the signaling molecule 2,'3'-cAMP ...

These risk factors can, in turn, activate intracellular signal pathways such as phosphatidylinositol 3-kinase (PI3K)/Akt, mitogen-activated protein kinase (MAPK), extracellular signal-regulated kinase ...