Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disease characterized primarily by the formation of heterotopic ...

Results The GCPM ecosystem coordinates a unique immunosuppressive pattern distinct from that of primary GC, which is dominated by a stroma-myeloid niche composed of SPP1+tumour-associated macrophages ...

Purpose: To characterize in mice of both genders with HFpEF the cardiac pro-inflammatory and the protective resident repair Mo. Methods: 12-week-old male and female C57BL/6N mice received HFD (60% ...

The biotechs teamed up to develop a method to engineer immune cells called macrophages to target solid tumors. Weekly dosing of the therapy, dubbed CAR-M, shrank lung and liver tumors in mice ...

Charged residues among the natural amino acids comprise the basic residues arginine (R), lysine (K), and histidine (H) or the acidic residues aspartic acid (D) and glutamic acid (E). We investigated ...