From the very moment an egg is fertilized, life begins with a remarkable process: cells start dividing and replicating to ...

From the very moment an egg is fertilized, life begins with a remarkable process: cells start dividing and replicating to make copies ...

Researchers from Osaka University have revealed some of the precise mechanisms by which erroneous cells are recognized, ...

Prostate cancer remains a global health challenge, ranking as the second most commonly diagnosed cancer among men. Although treatments like androgen ...

Another intriguing avenue of research involves combining PNC-27 with emerging cancer agent strategies, such as immunotherapy and gene editing. The peptide's potential to disrupt cancer cell membranes ...

Opna Bio AG has presented promising data regarding their EP300/CBP inhibitor OPN-6602 for the treatment of multiple myeloma (MM). The inhibition of EP300/CBP causes cell cycle arrest and apoptosis in ...

Up to the 1980s, cell death caused by drugs, chemicals, and other pathophysiologies was primarily considered necrosis. This ...

Extensive Scientific Evidence Supporting Growth Factor Receptor Bound Protein-2 (Grb2) as Fundamental Link in Insulin ResistanceReallocates ...

The evidence for the authors' claims is convincing, combining state-of-the-art conditional gene deletion in the mouse lens with histological and molecular approaches. This work should be of great ...

Sumitomo Pharma America, Inc. (SMPA) today presented new clinical data supporting further development of nuvisertib, an investigational small molecule being researched for the treatment of ...

Dysregulated cell signaling underlies various diseases, emphasizing the importance of understanding these pathways for ...

In this review, we provide a comprehensive summary of the processes involving Pin1 and its mechanisms in the context of cancer therapy. Pin1 enhances signaling pathways in a number of different human ...