However, its precise pathogenesis remains elusive. Consequently, researchers are dedicated to uncovering CI-AKI’s pathophysiology and signaling pathways, including inflammation, oxidative stress, ...

Today, apoptosis is implicated in a variety of ... of compounds that interact with specific components of cell signaling pathways, such as NF-κB and mitogen-activated protein kinases (MAPKs).

Dysregulated cell signaling underlies various diseases, emphasizing the importance of understanding these pathways for ...

Now, in eLife, Dean Sheppard and colleagues at the University of California San Francisco – including Imran Khan as first author – report the results of experiments on mice that explore the influence ...

Up to the 1980s, cell death caused by drugs, chemicals, and other pathophysiologies was primarily considered necrosis. This ...

From the very moment an egg is fertilized, life begins with a remarkable process: cells start dividing and replicating to ...

The research team initially identified Cul3 as a potential regulator in the Drosophila immune deficiency (IMD) signaling ...

Int J Mol Med, 5, 645-53. [4] Lettre and Hengartner (2006) Developmental apoptosis in C. elegans: a complex CEDnario. Nat Rev Mol Cell Biol, 2, 97-108. [5] Pecina-Slaus (2010) Wnt signal transduction ...

Prostate cancer remains a global health challenge, ranking as the second most commonly diagnosed cancer among men. Although treatments like androgen ...

The evidence for the authors' claims is convincing, combining state-of-the-art conditional gene deletion in the mouse lens with histological and molecular approaches. This work should be of great ...