Prostate cancer remains a global health challenge, ranking as the second most commonly diagnosed cancer among men. Although treatments like androgen ...
Aberrant activation of the Ras/Raf/MAPK/ERK kinase/extracellular signal-regulated kinase cascade and the VEGF pathway are commonly ... prevention of apoptosis, tumor invasion and neo-angiogenesis.
This paper presents the important discovery that lipid metabolic imbalance caused by Snail, an EMT-related transcription factor, contributes to the acquisition of chemoresistance in cancer cells.
When DNA damage is detected, p53 can either arrest the cell cycle or induce apoptosis, depending on the severity of the damage ... Keywords: p53 mutation, breast cancer, gain-of-function, therapy, ...
Another intriguing avenue of research involves combining PNC-27 with emerging cancer agent strategies, such as immunotherapy and gene editing. The peptide's potential to disrupt cancer cell membranes ...