which indicate that the antiangiogenic effects of bevacizumab might persist despite the development of resistance to first-line chemotherapy. For decades, cancer therapy has been rooted in the ...

However, lack of response to antiangiogenic drugs and adverse drug reactions leading to treatment suspension are critical clinical problems that need to be solved. Because antiangiogenic drugs act ...

ENA-78 = Epithelial neutrophil-activating peptide-78; FKN = Fractalkine; FLT3 = FMS-related tyrosine kinase 3; G-CSF = Granulocyte colony-stimulating factor; PD-ECGF = Platelet-derived endothelial ...

Angiopoietin-2 (ANGPT2) is a ligand of the receptor tyrosine kinase TIE2 (TEK). In conjunction with vascular endothelial growth factor (VEGF), ANGPT2-TIE2 signaling induces vascular sprouting.