Without Rosetta, determining a protein’s structure could take years, but with this computational approach ... As a proof of concept, they targeted EGFR, a protein often overexpressed in cancers, ...

The latest version of Google DeepMind and Isomorphic Labs’ AlphaFold model can predict the structure and relationships not only of proteins, but “all of life’s molecules”, according to its ...

Its alignment-free nature makes it much faster than traditional approaches, and the newly found remote homologs benefit our understanding of protein evolution, structure and function. This study ...

This interesting study presents valuable information on how human cytomegalovirus (HCMV) infection disrupts the activity of the TEAD1 transcription factor, leading to widespread chromatin alterations.

Fluorescence signals appear gradually with protein concentration for continuous monitoring. The fluorescence sensor amplified the fluorescence signal using an optical structure of the structure ...

Tumor cells transform fibroblasts into cancer-associated fibroblasts, which have an important immunosuppressive activity on which growth, invasion, and metastasis depend. These activated fibroblasts ...

Cell signalling is the mechanism by which stimuli are transmitted via a signalling cascade to effector molecules that orchestrate the appropriate response. Types of cell signalling pathways ...

Mutant RAS, they ... Oct. 31, 2024 — Researchers have shown that the IGFBP3 protein plays a relevant role in human lung development. The results of the study, which used organoids derived from ...

编者按在第75届美国肝病研究学会（AASLD）年会上，广西医科大学第一附属医院江建宁教授团队在乙型肝炎病毒感染相关肝细胞癌（HBV-HCC）、HBV抗病毒治疗领域共3项研究成果被大会收录，其中一项入选大会口头报告。该项研究成果揭示了HBV整合事件对长 ...