China’s drug regulator approved Alpha Biopharma Ltd.’s EGFR tyrosine kinase inhibitor (TKI), Zorifer (zorifertinib hydrochloride tablets; AZD-3759), as a first-line treatment for EGFR-mutated ...

Johnson & Johnson JNJ announced that the EMA’s Committee for Medicinal Products for Human Use (“CHMP”) recommended approving the combination of its intravenously administered EGFR/MET ...

A new BLA for Dato-DXd targets EGFR-mutated NSCLC, following withdrawal of a previous application based on ... who have progressed on or after one regimen of platinum-based chemotherapy and at least ...

Proton pump inhibitors (PPIs) are a class of medications used to treat conditions involving excess stomach acid, such as gastroesophageal reflux disorder (GERD) and stomach ulcers. They work by ...

The EGFR pathway regulates the Bax/Bcl-2 cascade in NSCLC. Increasing understanding of the molecular mechanisms of fundamental tumor progression has guided the development of numerous antitumor drugs.

“Preclinical data presented at the ENA conference highlighted ORIC-114's potential for superior potency and selectivity in targeting EGFR exon ... combinations with AR inhibitors for the ...

One class of ARTs, integrase inhibitors, has become a standard HIV treatment. Research shows they work well to keep the disease in check. Here’s what you need to know. Integrase inhibitors are ...

The term “protease inhibitor” refers to a class of medications rather than to a single medication. Specifically, they are antiviral drugs. But unlike the many, more common antiviral drugs that ...