Skin biopsies from EGFR inhibitor-treated and cicatricial alopecia patients revealed an active JAK ... be exploited by microbes leading to hair follicle inflammation and the consecutive destruction of ...

China’s drug regulator approved Alpha Biopharma Ltd.’s EGFR tyrosine kinase inhibitor (TKI), Zorifer (zorifertinib hydrochloride tablets; AZD-3759), as a first-line treatment for EGFR-mutated ...

Kim’s team revealed that once COVID-19 invades human cells, it quickly modifies the structure and function ... Using FDA-approved EGFR inhibitors, such as vandetanib and dacomitinib, the team ...

Instead, research is more focused on mechanisms of resistance to first-line TRK inhibitors. “There are now clear mechanisms of resistance with these molecules in the context of certain mutations,” he ...