Gene Park is a reporter for The Washington Post, covering video games and gaming culture. He joined The Post in 2015 as audience editor, and is a former reporter in the West Coast and Pacific region.
TYK Medicines Inc. has identified proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase-binding moiety covalently bonded to an EGFR (mutant)-targeting moiety through a ...
Kebilidi is intended as a gene replacement therapy that is directly administered to the putamen, a structure located in the center of the brain, through a minimally invasive neurosurgical procedure.
Weill Cornell Medicine researchers have determined the full-length structure of a blood pressure-regulating hormone receptor for the first time, uncovering how it functions, which may enable better ...
A new BLA for Dato-DXd targets EGFR-mutated NSCLC, following withdrawal of a previous application based on TROPION-Lung01 trial data. The new submission is supported by phase 2 TROPION-Lung05 trial ...
In this work, we engineer a CAR T cell against epidermal growth factor receptor variant III (EGFRvIII ... cancer cells that carry the recognized structure. The CAR T cells developed by Hutter ...
Children with the expanded gene also had larger cerebral volumes and greater cortical surface area and folding. After this initial peak, a prolonged deterioration was seen in both brain function and ...
The clinical features of the patients were retrieved from the hospital information system. Inclusion criteria for this study were: (1) patients with confirmed EGFR gene mutation status and ...
Through further research, the team identified a key gene, named SM1, that plays a crucial role in controlling the development of rice leaf veins. The SM1 gene encodes a litter zipper protein that ...