TYK Medicines Inc. has identified proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase-binding moiety covalently bonded to an EGFR (mutant)-targeting moiety through a ...

"We manufacture so-called 'gene ferries,' into which all kinds of ... The specific focus was on how changes in polymer structure and environmental conditions impact particle formation.

Study uses spatial transcriptomics to map intratumoral heterogeneity and microenvironmental dynamics in triple-negative ...

Oct. 28, 2024 — Using state-of-the-art technology, researchers have identified several specific steps needed for CRISPR to become active and perform its gene editing function. These preclinical ...

"We manufacture so-called 'gene ferries,' into which all kinds of ... The specific focus was on how changes in polymer structure and environmental conditions impact particle formation.

Scientists at Inventisbio Co. Ltd. and Inventisbio LLC have divulged E3 ubiquitin-protein ligase CBL-B (CBLB) inhibitors reported to be useful for the treatment of cancer.

Gene therapy involves the introduction of new genes into cells, to restore or add gene expression, for the purpose of treating disease. Most commonly a mutated gene is replaced with DNA encoding a ...

It seeks to understand the process of trait inheritance from parents to offspring, including the molecular structure and function of genes, gene behaviour in the context of a cell or organism (e.g ...

This interesting study presents valuable information on how human cytomegalovirus (HCMV) infection disrupts the activity of the TEAD1 transcription factor, leading to widespread chromatin alterations.

This transaction affects the share capital structure, with 125,404,415 issued ordinary shares now in circulation. Investors should note this change when assessing their interest in the company.

Dr. Omisakin attributed this volatility to two fundamental issues: the economy’s flawed structure and the absence of a coherent economic philosophy. “The structure of the economy has been ...