This “exposure” yields many 2-D images of the molecules at different angles, which algorithms then merge into one 3-D model. At first cryo-EM rendered molecules as vague lumps, so some ...

This work will be of high interest to a broad swathe of scientists studying native macromolecules present at low concentrations in cells. Cryo-EM single-particle analyses typically require target ...

In a groundbreaking development, researchers from the United States and Denmark have successfully captured 3D images of ...

For the first time, researchers at the University of California San Diego report near-atomic-resolution images and video of nitrogenase during catalysis using cryogenic electron microscopy (cryoEM).