Type 2 diabetes (T2D) and obesity (OB) are associated with chronic low-grade inflammation and increased fracture risk. In vitro studies showed that inflammation induces bone erosion and inhibits bone ...

Hypothesis: Atrial myopathy due to the LMNA-S143P mutation, creates an arrhythmogenic substrate for AF by causing ion channel and chromatin remodeling. Approach: We performed clinical phenotyping and ...

Allarity maintains a cash balance of $18.5 million, sufficient to advance and accelerate stenoparib's clinical development ...

Surrozen, Inc. (“Surrozen” or the “Company”) (Nasdaq: SRZN), a company pioneering targeted therapeutics that selectively activate the Wnt pathway for tissue repair and regeneration, today announced a ...

Hair loss significantly impacts patients' quality of life, and it may be nonscarring or scarring. Etiologically, hair loss ...

The AMPKα-HNF4α-WNT5A signalling cascade represents a potentially targetable pathway for drug development ... Development of therapies that specifically target the AMPK–HNF4α–WNT signal cascade would ...

Low-dose oral minoxidil is emerging as a treatment for hair loss, with a need for expert guidelines on its safety and ...