First, exposure to the AAV vector triggers the development of ... of observed liver cell death and require the use of combined immunosuppression treatments. Importantly, some patients have not ...
reversal of tumor immunosuppression and the recruitment and activation of additional effector cell types and cytotoxic activities (Fig. 1). Certain vector genes are engineered to be expressed only ...
In the USA and some other countries, the costs of immunosuppression make transplantation unavailable for some medically viable transplant candidates, and for others who receive a transplant ...