Tumor cells transform fibroblasts into cancer-associated fibroblasts, which have an important immunosuppressive activity on which growth, invasion, and metastasis depend. These activated fibroblasts ...
CloseCurlyDoubleQuote; SNS-101 is a conditionally active antibody designed to selectively target the immune checkpoint VISTA (V-domain Ig suppressor of T cell activation) within the tumor ...
a conditionally active antibody designed to block the V-domain Ig suppressor of T cell activation (VISTA) checkpoint selectively within the low pH tumor microenvironment, where VISTA acts as a ...
Amit Sharma as the first author, has identified GLUT3, a glucose transporter, as essential to the suppressive function of regulatory T cells (Tregs) in the tumor microenvironment (TME).
The tumor microenvironment (TME) is one of the most formidable obstacles in the fight against cancer. While therapies that target cancer cells have been revolutionary, many patients still do not ...
Watch: James Van Der Beek Describes Moment He Received Stage 3 Cancer Diagnosis: "I Went Into Shock" James Van Der Beek is getting used to the unknowns that accompany his cancer diagnosis.
An app developed by the right-wing nonprofit True the Vote to crowdsource claims of voter fraud contained a security flaw that exposed the email addresses of all users who posted or commented on ...