So far, no treatment has been able to make this aggressive tumor permanently disappear. The tumor cells are too varied, and the microenvironment ... Tumor Suppressor Protein Par-4 Triggers Unique ...

Research reveals SLC13A3's role in tumor cell survival and immune therapy resistance, highlighting its potential as a target ...

The interplay between hypoxic and acidic conditions in the tumor microenvironment is unclear. Here, the authors show that hypoxic and acidic tumor cells do not fully overlap and display a ...

Scientists at Pohang University of Science and Technology (POSTECH) and ShanghaiTech University have achieved a breakthrough ...

In a recent study published in Nature, researchers investigate the spatial organization of cancer cells and the tumor microenvironment ... early region 2 binding factor (E2F), across the tumor ...

Tumor cells transform fibroblasts into cancer-associated fibroblasts, which have an important immunosuppressive activity on which growth, invasion, and metastasis depend. These activated fibroblasts ...

Patients with HGSOC showed significant suppression of TAGLN2 in CD 8+ T cells within ascites and the tumor microenvironment. The study identified that the inositol-requiring enzyme one alpha ...

“The ovarian tumor microenvironment (TME) is commonly in an immune-suppressed state with local exclusion and/or suppression of T cells, which is considered a contributing factor to the poor ICB ...

Several studies have pointed out that the complex intercellular communication network in the immune microenvironment of HCC regulates tumor escape and ... including regulatory T (Treg) cells, ...