The outer membrane (chorion) and trophoblast layer of the placenta are derived from the trophoectoderm of the blastocyst cells. Other extra-embryonic tissues, including the amnion (inner membrane ...

The aim of this Research Topic is to provide an overview of the physiology and Pathophysiology of the placenta in order to better understand its development under normal and pathological conditions.

We have found that these cells initially lose their stem cell characteristics and change their appearance from stem cells to trophoblast (placental) cells. In addition, we conducted a study over 12 ...

8–12 In a normal pregnancy, the ongoing complement activation is strictly regulated by membrane regulators decay-accelerating factor, membrane cofactor protein and CD59 located on the trophoblast ...

研究胎盘发育机制对深入探究人类孕早期特征和女性生殖健康意义重大。科学家通过构建“迷你胎盘”（滋养层细胞类器官）揭示出胎盘发育过程及其与子宫内膜的相互作用。相关研究成果刊发在《Cell Stem ...

This important study advances our understanding of the mechanisms controlling lipid flux and ion permeation in the TMEM16 and OSCA/TMEM63 family channels. The study provides compelling new evidence ...

According to the literature, exposure to drugs before implantation can lead to poor and slow embryo development, increased apoptosis, decreased cell count, epigenetic changes in both embryo and ...

The investigators found that maternal RSV vaccination at least 5 weeks prior to delivery led to the most efficient transfer of maternal antibodies across the placenta to the newborn, compared with ...