Transforming growth factor-beta (TGF-β), a well-known morphogen ... of Sciences revealed the molecular mechanism of TGF-β ...

Inactivating mutations in the gene encoding transforming growth factor β (TGF-β), or components of its signal-transduction pathway, are known to enhance tumor proliferation and invasiveness ...

The transforming growth factor beta (TGF-beta) pathway regulates vascular remodeling and mutations in its receptor genes, TGFBR1 and TGFBR2, cause syndromes with thoracic aortic aneurysm (TAA).

Dysfunctional TGF-Beta is a major contributor to lung diseases ... in 2016 to develop therapeutics for targets in the Wnt pathway, a key signaling pathway that is involved in embryo development ...

Currently, we are working with Orange Grove Bio and Station 41 to continue this drug development pathway. One of our therapeutic targets is renal fibrosis. To this end, Orange Grove Bio has ...

Significantly higher levels of the miRNA molecule miR-3591-5p were seen in those with CHD and moderate to severe PAH than ...

Jefferies initiated coverage of Keros Therapeutics (KROS) with a Buy rating and $107 price target The firm says Keros has expertise in the TGF-beta pathway, which plays roles in blood, lung and ...

Surrozen, Inc. (“Surrozen” or the “Company”) (Nasdaq: SRZN), a company pioneering targeted therapeutics that selectively activate the Wnt pathway for tissue repair and regeneration, today announced a ...