Sickle cell disease (SCD) is a pressing global health issue, with rising cases and mortality, especially in low- and middle-income countries (LMICs). Hydroxyurea, a cost-effective treatment for ...

The disease gets its name because when you have SCD, your red blood cells look like a sickle, which is a C-shaped farm tool. Normal red blood cells are round and pliable. With sickle cell ...

The majority of SCD patients given Lyfgenia in clinical trials remained free of vaso-occlusive events (VOEs) following ...

Nigerian woman opens up about the struggles of living with sickle cell disease, sharing her story to raise genotype ...

A breakthrough at the Lagos University Teaching Hospital, Idi-Araba, has brought cheery news to people with sickle cell disease. LUTH doctors working with an NGO, Sickle Cell Foundation of Nigeria ...

Cyclosporin H Improves the Transduction of CD34+ Cells with an Anti-Sickling Globin Vector, a Possible Therapeutic Approach for Sickle Cell Disease. Credit: Mary Ann Liebert, Inc.

MiNA Therapeutics Limited, the pioneer in small activating RNA (RNAa) therapeutics, today presented new pre-clinical data for its lead RNA activation program for the treatment of sickle cell disease, ...

As he got older, he learned he had sickle cell disease: His red blood cells were forming sickle shapes and getting stuck in his blood stream, preventing oxygen from reaching his tissues.

MTL-HBG is an RNAa medicine designed to increase transcription of the gamma globin gene (HBG), enabling people with sickle cell disease to produce enhanced levels of fetal hemoglobin (HbF).

there are an estimated 11,000 individuals living with Sickle Cell Disease in California. The Networking California for Sickle Cell Care network serves 960 adults across 12 clinical sites and two ...

The most-read gene therapy articles included topics on FDA approvals, chimeric antigen receptor T-cell therapies, the ...